Preliminary characterization of PRESAGE®for 3D dosimetry of 62 MeV proton beam
نویسندگان
چکیده
منابع مشابه
Calculating Variations in Biological Effectiveness for a 62 MeV Proton Beam
A biophysical model of radiation-induced cell death and chromosome aberrations [called BIophysical ANalysis of Cell death and chromosome Aberrations (BIANCA)] was further developed and applied to therapeutic protons. The model assumes a pivotal role of DNA cluster damage, which can lead to clonogenic cell death following three main steps: (i) a DNA "cluster lesion" (CL) produces two independent...
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Background: High and intermediate energy protons are not able to form a track in a solid state nuclear track detector (SSNTD) directly. However, such tracks can be formed through secondary particles created during primary radiation nuclear reactions in a SSNTD. Materials and Methods: The protons with primary energies of 9.6 and 30 MeV available at the cyclotron accelerator with corresponding lo...
متن کاملPRELIMINARY STUDY OF PROTON BEAM TRANSPORT IN A 10 MeV DIELECTRIC WALL ACCELERATOR*
A novel proton accelerator based on Dielectric Wall Accelerator (DWA) technology is being developed at Institute of Fluid Physics (IFP). The accelerating gradient will be 25 MV/m or even higher based on current high gradient insulator (HIG) performance. Theoretical study and numerical simulation of accelerating the proton beam to 10 MeV by virtual travelling wave method are presented in this pa...
متن کاملRelative biological effectiveness variation along monoenergetic and modulated Bragg peaks of a 62-MeV therapeutic proton beam: a preclinical assessment.
PURPOSE The biological optimization of proton therapy can be achieved only through a detailed evaluation of relative biological effectiveness (RBE) variations along the full range of the Bragg curve. The clinically used RBE value of 1.1 represents a broad average, which disregards the steep rise of linear energy transfer (LET) at the distal end of the spread-out Bragg peak (SOBP). With particul...
متن کاملMonte Carlo water-equivalence study of two PRESAGE formulations for proton beam dosimetry
PRESAGE is a radiochromic solid dosimeter which shows promising potential for 3D proton beam dosimetry. Since an idea dosimeter should be water-equivalent, total depth dose distributions in two PRESAGE formulations irradiated by a 62 MeV proton beam were compared with that in water using GEANT4 Monte Carlo simulations. The dose delivered by secondary particles was also calculated. Our results s...
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ژورنال
عنوان ژورنال: Journal of Physics: Conference Series
سال: 2013
ISSN: 1742-6596
DOI: 10.1088/1742-6596/444/1/012058